Full text articles

Fialová D, Laffon B, Marinković V, Tasić L, Doro P, Sόos G, Mota J, Dogan S, Brkić J, Teixeira JP, Valdiglesias V, Costa S

Medication use in older patients and age-blind approach: narrative literature review (insufficient evidence on the efficacy and safety of drugs in older age, frequent use of PIMs and polypharmacy, and underuse of highly beneficial nonpharmacological strat

European Journal of Clinical Pharmacology, 2019 Jan 4. doi: 10.1007/s00228-018-2603-5. [Epub ahead of print]
Arnold K, Teixeira JP, Mendes A, Madureira J, Costa S, Salamova A

A pilot study on semivolatile organic compounds in senior care facilities: Implications for older adult exposures.

Environ Pollut, 2018 May 31;240:908-915. doi: 10.1016/j.envpol.2018.05.017. [Epub ahead of print]
Torres P, Ferreira J, Monteiro A, Costa S, Pereira MC, Madureira J, Mendes A, Teixeira JP

Air pollution: A public health approach for Portugal.

Science of The Total Environment, Volume 643, 1 December 2018, Pages 1041-1053
Bessada SMF, Barreira JCM, Santos J, Costa S, Pimentel FB, Bessa MJ, Teixeira JP, Oliveira MBPP

Evaluation of the cytotoxicity (HepG2) and chemical composition of polar extracts from the ruderal species Coleostephus myconis (L.) Rchb.f.

J Toxicol Environ Health A, 2017 May 19:1-10. doi: 10.1080/15287394.2017.1286915. [Epub ahead of print]

Recent developments on Occupational and Environmental Toxicology.

J Toxicol Environ Health A, 2017 Oct 2:1. doi: 10.1080/15287394.2017.1382124. [Epub ahead of print]
Abreu A, Costa C, Silva S, Morais S, do Carmo Pereira M, Fernandes A, Moraes de Andrade V, Teixeira JP, Costa S

Wood smoke exposure of Portuguese wildland firefighters: DNA and oxidative damage evaluation.

J Toxicol Environ Health A, 2017 May 19:1-9. doi: 10.1080/15287394.2017.1286896. [Epub ahead of print]
Esteves FC, Teixeira E, Amorim T, Costa C, Pereira CC, Fraga S, De Andrade VM, Teixeira JP, Costa S

Assessment of DNA damage in a group of professional dancers during a 10-month dancing season.

J Toxicol Environ Health A, 2017 Jul 11:1-8. doi: 10.1080/15287394.2017.1331599. [Epub ahead of print]
Sánchez-Flores M, Marcos-Pérez D, Costa S, Teixeira JP, Bonassi S, Pásaro E, Laffon B, Valdiglesias V

Oxidative stress, genomic features and DNA repair in frail elderly: A systematic review.

Ageing Res Rev, 2017 May 6;37:1-15. doi: 10.1016/j.arr.2017.05.001. [Epub ahead of print]
Costa S, Ceppi M, Costa C, Silva S, Pereira C, Laffon B, Bonassi S, Teixeira JP

The cytokinesis-block micronucleus (CBMN) assay in human populations exposed to styrene: A systematic review and meta-analysis.

Mutat Res, 2016 Oct - Dec;770(Pt A):92-105. doi: 10.1016/j.mrrev.2016.06.003. Epub 2016 Jun 23.
Valdiglesias V, Fernández-Bertólez N, Kiliç G, Costa C, Costa S, Fraga S, Bessa MJ, Pásaro E, Teixeira JP, Laffon B

Are iron oxide nanoparticles safe? Current knowledge and future perspectives.

J Trace Elem Med Biol, 2016 Dec;38:53-63. doi: 10.1016/j.jtemb.2016.03.017. Epub 2016 Mar 31.
Silveira C, Roebeling P, Lopes M, Ferreira J, Costa S, Teixeira JP, Borrego C, Miranda AI

Assessment of health benefits related to air quality improvement strategies in urban areas: An Impact Pathway Approach.

J Environ Manage, 2016 Dec 1;183(Pt 3):694-702. doi: 10.1016/j.jenvman.2016.08.079. Epub 2016 Sep 15.
Miranda AI, Ferreira J, Silveira C, Relvas H, Duque L, Roebeling P, Lopes M, Costa S, Monteiro A, Gama C, Sá E, Borrego C, Teixeira JP

A cost-efficiency and health benefit approach to improve urban air quality.

Sci Total Environ, 2016 Nov 1;569-570:342-51. doi: 10.1016/j.scitotenv.2016.06.102. Epub 2016 Jun 24.
Costa S, Carvalho S, Costa C, Coelho P, Silva S, Santos LS, Gaspar JF, Porto B, Laffon B, Teixeira JP

Increased levels of chromosomal aberrations and DNA damage in a group of workers exposed to formaldehyde.

Mutagenesis, 2015 Jul;30(4):463-73. doi: 10.1093/mutage/gev002. Epub 2015 Feb 22.
Costa C, Silva S, Neves J, Coelho P, Costa S, Laffon B, Snawder J, Teixeira JP

Micronucleus frequencies in lymphocytes and reticulocytes in a pesticide-exposed population in Portugal

J Toxicol Environ Health, 74(15-16):960-70. doi: 10.1080/15287394.2011.582024.
Botelho M, Costa C, Silva S, Costa S, Oliveira P, Teixeira JP

Effects of titanium dioxide nanoparticles in human gastric epithelial cells in vitro

Biomed Pharmacother, 2014 Feb;68(1):59-64. doi: 10.1016/j.biopha.2013.08.006. Epub 2013 Aug 23.
Costa C, García-Lestón J, Costa S, Silva S, Pingarilho M, Valdiglesias V, Mattei F, Dall'Armi V, Bonassi S, Laffon B, Snawder J, Teixeira JP

Is organic farming safer to farmers' health? A comparison between organic and traditional farming.

Toxicol Lett, Oct 15;230(2):166-76. doi: 10.1016/j.toxlet.2014.02.011. Epub 2014 Feb 24.
Godschalk RW, Ersson C, Ferlińska M, Teixeira JP, Costa S, Jones GD, Higgins JA, Möller L, Forchhammer L, Loft S, Collins AR, van Schooten FJ, Valdiglesias V, Cooke M, Mistry V, Karbaschi M, Phillips DH, Sozeri O, Routledge MN, Nelson-Smith K, Riso P, Porrini M, López de Cerain A, Azqueta A, Matullo G, Allione A, Møller P

Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories

Mutagenesis, 2014 Jul;29(4):241-9. doi: 10.1093/mutage/geu012. Epub 2014 Apr 15.
Costa S, Ferreira J, Silveira C, Costa C, Lopes D, Relvas H, Borrego C, Roebeling P, Miranda AI, Teixeira JP

Integrating health on air quality assessment--review report on health risks of two major European outdoor air pollutants: PM and NO₂.

J Toxicol Environ Health, 2014;17(6):307-40. doi: 10.1080/10937404.2014.946164.
Coelho P, García-Lestón J, Costa S, Costa C, Silva S, Fuchs D, Dall´Armi V, Zoffoli R, Bonassi S, Pásaro E, Laffon B, Teixeira JP

Immunological alterations in individuals exposed to metal(loid)s in the Panasqueira mining area, Central Portugal

Sci Total Environ, 2014 Mar 15;475:1-7. doi: 10.1016/j.scitotenv.2013.12.093. Epub 2014 Jan 11.
Costa S, Brandão F, Coelho M, Costa C, Coelho P, Silva S, Porto B, Teixeira JP

Micronucleus frequencies in lymphocytes and buccal cells in formaldehyde exposed workers

WIT Transactions on Biomedicine and Health, 2013, 16: 83-94.
Lorenzo Y, Costa S, Collins AR, Azqueta A

The comet assay, DNA damage, DNA repair and cytotoxicity: hedgehogs are not always dead

Mutagenesis, 2013 Jul;28(4):427-32. doi: 10.1093/mutage/get018. Epub 2013 Apr 29.
Coelho P, García-Lestón J, Costa S, Costa C, Silva S, Dall´Armi V, Zoffoli R, Bonassi S, Lima JP, Gaspar JF, Pásaro E, Laffon B, Teixeira JP

Genotoxic effect of exposure to metal(loid)s. A molecular epidemiology survey of populations living and working in Panasqueira mine area, Portugal

Environ Int, 2013 Oct;60:163-70. doi: 10.1016/j.envint.2013.08.014. Epub 2013 Sep 13.
Azqueta A, Costa S, Lorenzo Y, Bastani NE, Collins AR

Vitamin C in cultured human (HeLa) cells: lack of effect on DNA protection and repair.

Nutrients, 2013 Apr 9;5(4):1200-17. doi: 10.3390/nu5041200.
Ersson C, Møller P, Forchhammer L, Loft S, Azqueta A, Godschalk RW, van Schooten FJ, Jones GD, Higgins JA, Cooke MS, Mistry V, Karbaschi M, Phillips DH,Sozeri O, Routledge MN, Nelson-Sm, Teixeira JP, Costa S, Corcuera LA, López de Cerain A, Laffon B, Valdiglesias V, Collins AR, Möller L

An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells

Mutagenesis, 2013 May;28(3):279-86. doi: 10.1093/mutage/get001. Epub 2013 Feb 27.
de Mello RA, Ferreira M, Soares-Pires F, Costa S, Cunha J, Oliveira P, Hespanhol V, Reis RM.

The impact of polymorphic variations in the 5p15, 6p12, 6p21 and 15q25 Loci on the risk and prognosis of portuguese patients with non-small cell lung cancer.

PLoS One, 2013 Sep 6;8(9):e72373. doi: 10.1371/journal.pone.0072373. eCollection 2013.
Coelho P, Costa S, Silva S, Walter A, Ranville J, Sousa AC, Costa C, Coelho M, García-Lestón J, Pastorinho MR, Laffon B, Pásaro E, Harrington C, Taylor A, Teixeira JP

Metal(loid) levels in biological matrices from human populations exposed to mining contamination - Panasqueira Mine (Portugal

J Toxicol Environ Health, 75:893–908
Forchhammer L, Johansson C, Loft S, Möller L, Godschalk RW, Langie SA, Jones GD, Kwok RW, Collins AR, Azqueta A, Phillips DH, Sozeri O, Stepnik M,Palus J, Vogel U, Wallin H, Routledge MN,, Teixeira JP, Costa S, Møller P

Variation in the measurement of DNA damage by comet assay measured by the ECVAG inter-laboratory validation trial

Mar;25(2):113-23. doi: 10.1093/mutage/gep048. Epub 2009 Nov 12.
Teixeira JP, Gaspar JF, Coelho P, Costa C, Silva S, Costa S, Da Silva S, Laffon B, Pásaro E, Rueff J

Cytogenetic and DNA damage on workers exposed to styrene

Mutagenesis, Nov;25(6):617-21. doi: 10.1093/mutage/geq049. Epub 2010 Aug 20.
Costa S, Coelho P, Costa C, Da Silva S, Mayan O, Santos LS, Gaspar JF, Teixeira JP

Genotoxic damage in pathology anatomy laboratory workers exposed to formaldehyde

Toxicology, Oct 30;252(1-3):40-8. doi: 10.1016/j.tox.2008.07.056. Epub 2008 Jul 31

Book Chapters


“Frailty Syndrome – An Emergent Concern of Unknown Causes.”

2018, In: Elderly Care: Options, Challenges and Trends (Nova Science Publishers, Inc), ISBN: 978-1-53613-462-9

“Human Cytogenetic Biomonitoring”.

2018, In: An Essential Guide to Cytogenetics (Nova Science Publishers, Inc), ISBN: 978-1-53613-371-4

“Indoor Environments and Elderly Health” .

2018, In: Elderly Care: Options, Challenges and Trends (Nova Science Publishers, Inc), ISBN: 978-1-53613-462-9


Occupational Exposure to formaldehyde. Genotoxic damage and susceptibility evaluation in a pathology laboratory workers

Solange Costa
Supervisor: João Paulo Teixeira