Full text articles

Fialová D, Laffon B, Marinković V, Tasić L, Doro P, Sόos G, Mota J, Dogan S, Brkić J, Teixeira JP, Valdiglesias V, Costa S

Medication use in older patients and age-blind approach: narrative literature review (insufficient evidence on the efficacy and safety of drugs in older age, frequent use of PIMs and polypharmacy, and underuse of highly beneficial nonpharmacological strat

European Journal of Clinical Pharmacology, 2019 Jan 4. doi: 10.1007/s00228-018-2603-5. [Epub ahead of print]
Laffon B, Fernández-Bertólez N, Costa C, Brandão F, Teixeira JP, Pásaro E, Valdiglesias V

Cellular and Molecular Toxicity of Iron Oxide Nanoparticles.

Adv Exp Med Biol, 2018;1048:199-213. doi: 10.1007/978-3-319-72041-8_12.
Fernández-Bertólez N, Costa C, Brandão F, Kiliç G, Teixeira JP, Pásaro E, Laffon B, Valdiglesias V

Neurotoxicity assessment of oleic acid-coated iron oxide nanoparticles in SH-SY5Y cells.

Toxicology, 2018 Jun 6. pii: S0300-483X(18)30111-2. doi: 10.1016/j.tox.2018.06.003. [Epub ahead of print]
Fernández-Bertólez N, Costa C, Brandão F, Kiliç G, Duarte JA, Teixeira JP, Pásaro E, Valdiglesias V, Laffon B

Toxicological assessment of silica-coated iron oxide nanoparticles in human astrocytes.

Food Chem Toxicol, 2018 Apr 27. pii: S0278-6915(18)30281-3. doi: 10.1016/j.fct.2018.04.058. [Epub ahead of print]
Valdiglesias V, Marcos-Pérez D, Lorenzi M, Onder G, Gostner JM, Strasser B, Fuchs D, Bonassi S

Immunological alterations in frail older adults: A cross sectional study.

Exp Gerontol, 2018 Sep 18;112:119-126. doi: 10.1016/j.exger.2018.09.010. [Epub ahead of print]
Sánchez-Flores M, Marcos-Pérez D, Costa S, Teixeira JP, Bonassi S, Pásaro E, Laffon B, Valdiglesias V

Oxidative stress, genomic features and DNA repair in frail elderly: A systematic review.

Ageing Res Rev, 2017 May 6;37:1-15. doi: 10.1016/j.arr.2017.05.001. [Epub ahead of print]
Laffon B, Fernández-Bertólez N, Costa C, Pásaro E, Valdiglesias V

Comparative study of human neuronal and glial cell sensitivity for in vitro neurogenotoxicity testing.

Food Chem Toxicol, 2017 Feb 4;102:120-128. doi: 10.1016/j.fct.2017.02.005. [Epub ahead of print]
Valdiglesias V, Maseda A, Lorenzo-López L, Pasaro E, Millán-Calenti JC, Laffon B

Is Salivary Chromogranin A a Valid Psychological Stress Biomarker During Sensory Stimulation in People with Advanced Dementia?

J Alzheimer Dis, 2017;55(4):1509-1517. doi: 10.3233/JAD-160893.
Laffon B, Pásaro E, Valdiglesias V

Effects of exposure to oil spills on human health: Updated review.

J Toxicol Environ Health B Crit Rev, 2016;19(3-4):105-28. doi: 10.1080/10937404.2016.1168730. Epub 2016 May 24.
Kiliç G, Costa C, Fernández-Bertólez N, P, Pásaro E, Teixeira JP, Laffon B, Valdiglesias V

In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells

Toxicology Res, 2016 vol 5, 4, 235
Valdiglesias V, Fernández-Bertólez N, Kiliç G, Costa C, Costa S, Fraga S, Bessa MJ, Pásaro E, Teixeira JP, Laffon B

Are iron oxide nanoparticles safe? Current knowledge and future perspectives.

J Trace Elem Med Biol, 2016 Dec;38:53-63. doi: 10.1016/j.jtemb.2016.03.017. Epub 2016 Mar 31.
Lorenzi M, Lorenzi T, Marzetti E, Landi F, Vetrano DL, Settanni S, Antocicco M, Bonassi S, Valdiglesias V, Bernabei R, Onder G

Association of frailty with the serine protease HtrA1 in older adults.

Exp Gerontol, 2016 Aug;81:8-12. doi: 10.1016/j.exger.2016.03.019. Epub 2016 Apr 4.
Costa C, Brandão F, Bessa MJ, Costa S, Valdiglesias V, Kiliç G, Fernández-Bertólez N, Quaresma P, Pereira E, Pásaro E, Laffon B, Teixeira JP

In vitro cytotoxicity of superparamagnetic iron oxide nanoparticles on neuronal and glial cells. Evaluation of nanoparticle interference with viability tests.

J Appl Toxicol, 2016 Mar;36(3):361-72. doi: 10.1002/jat.3213. Epub 2015 Jul 26.
Maseda A, Gómez-Caamano S, Lorenzo-López L, López-López R, Diego-Diez C, Sanluís-Martínez V, Valdiglesias V, Millán-Calenti JC

Health determinants of nutritional status in community-dwelling older population: the VERISAÚDE study.

Public Health Nutr , 2016 Aug;19(12):2220-8. doi: 10.1017/S1368980016000434. Epub 2016 Mar 15.
Prego-Faraldo MV, Valdiglesias V, Laffon B, Mendez J, Eirin-Lopez JM

Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis.

Toxins (Basel), 2016 May 24;8(6). pii: E159. doi: 10.3390/toxins8060159.
Valdiglesias V, Bonassi S, Dell'Armi V, Settanni S, Celi M, Mastropaolo S, Antocicco M, Fini M, Onder G

Micronucleus frequency in peripheral blood lymphocytes and frailty status in elderly. A lack of association with clinical features.

Mutat Res, 2015 Oct;780:47-54. doi: 10.1016/j.mrfmmm.2015.07.010. Epub 2015 Jul 29.
Sánchez-Flores M, Pásaro E, Bonassi S, Laffon B, Valdiglesias V

γH2AX assay as DNA damage biomarker for human population studies: defining experimental conditions.

Toxicol Sci, 2015 Apr;144(2):406-13. doi: 10.1093/toxsci/kfv011. Epub 2015 Jan 22.
Prego-Faraldo MV, Valdiglesias V, Laffon B, Eirin-Lopez JM, Méndez JM

In Vitro Analysis of Early Genotoxic and Cytotoxic Effects of Okadaic Acid in Different Cell Types of the Mussel Mytilus galloprovincialis.

J Toxicol Environ Health A, 2015;78(13-14):814-24. doi: 10.1080/15287394.2015.1051173.
Valdiglesias V, Sánchez-Flores M, Maseda A, Marcos-Pérez D, Millan-Calenti JC, Pásaro E, Lorenzo-López L, Laffon B

Lymphocyte Subsets in a Population of Nonfrail Elderly Individuals.

J Toxicol Environ Health A, 2015;78(13-14):790-804. doi: 10.1080/15287394.2015.1051170.

Book Chapters


“Frailty Syndrome – An Emergent Concern of Unknown Causes.”

2018, In: Elderly Care: Options, Challenges and Trends (Nova Science Publishers, Inc), ISBN: 978-1-53613-462-9