Revisiting the TB-Task Force of the Greater Lisbon 2000 to 2012: A successful laboratory, clinical and public health initiative in the fight against drug-resistant tuberculosis in Lisboa.
02:00pm to 04:00pm

The TB Task Force of Greater Lisbon (2000-2012), granted with the support of the Gulbenkian Foundation, afforded the basis for determining the mycobacteriological laboratory needs of 12 Hospitals of the Greater Lisbon Area and the surrounding communities dealing with tuberculosis. The principal objective for this group was to apply the same programme that was developed for New York City in the 1990's and which was proven to be effective in reducing the rate of new cases of pulmonary tuberculosis and especially drug resistant tuberculosis to the lowest level ever. This Fast Track Programme used the most modern technology at that time (reverse probe hybridization for drug resistance detection in 24 hours) and automatic instrumentation (fluorimetric BACTEC 960 system) that reduced the turn-around time to a bare minimum of 24 hours for direct detection of Tb and Rir resistant-TB and 20 days for the full report (ID+DST). Also created mechanisms for  the effective and timely communication to the physcian of the most important results that are needed for the effective isolation and therapy of the patient who is infected with TB or DR-TB. The goals were therefore to provide complete identification and preliminary information on drug susceptibility of the causative organism within 24 to 48 hours and complete antibiotic susceptibility results within 20 days in an integrated network of TB laboratories and hospitals that allowed the reduction of the excess of 35% of MDR-TB  in Lisbon in 2000 to less than 3.5% in 2012. A successful network that exceeded the time of the project(s) support and still are nowadays the cornerstone of the Hospital TB laboratory diagnosis network in the Greater Lisbon Area that maintains MDR-TB under control.

The seminar is free, and all are welcome (including members of the public) without needing to book a place.

Language: English

Miguel Viveiros
Unit of Medical Microbiology (Group of Mycobacteriology) of the Instituto de Higiene e Medicina Tropical da Universidade Nova de Lisboa.

Miguel Viveiros -  Biologist, expert in Medical Microbiology, Full Professor with Habilitation in Biomedical Sciences (Speciality Microbiology)  in the Unit of Medical Microbiology (Group of Mycobacteriology) of the Instituto de Higiene e Medicina Tropical da Universidade Nova de Lisboa.   Academic activities in support of the mission and institutional strategy of teaching and capacity building for the Community of Portuguese Language Countries (CPLP) in Biomedical Sciences, International Health and Tropical Medicine. Scientific activity devoted to the early diagnosis of active or latent tuberculosis (TB) infections as well as the development of new therapeutical approaches to deal with drug resistant bacterial infections.  More than 130 studies published in peer review national and international journals in mycobacteriology, bacteriology, resistance to antibiotics, microbial genetics, molecular epidemiology and immunology.