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Brandão F, Fernández-Bertólez N, Rosário F, Bessa MJ, Fraga S, Pásaro E, Teixeira JP, Laffon B, Valdiglesias V, Costa C

Genotoxicity of TiO2 Nanoparticles in Four Different Human Cell Lines (A549, HEPG2, A172 and SH-SY5Y).

Nanomaterials (Basel), 2020 Feb 27;10(3). pii: E412. doi: 10.3390/nano10030412.
Bessa MJ, Brandão F, Viana M, Gomes JF, Monfort E, Cassee FR, Fraga S, Teixeira JP

Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects.

Environ Res, 2020 May;184:109297. doi: 10.1016/j.envres.2020.109297. Epub 2020 Feb 24.
Pereira I, Fraga S, Maltez L, Requicha J, Guardão L, Oliveira J, Prada J, Alves H, Santos JD, Teixeira JP, Oliveira MBPP

In vivo systemic toxicity assessment of an oxidized dextrin-based hydrogel and its effectiveness as a carrier and stabilizer of granular synthetic bone substitutes.

J Biomed Mater Res A, 2019 Mar 28. doi: 10.1002/jbm.a.36683. [Epub ahead of print]
Dorier M, Tisseyre C, Dussert F, Béal D, Arnal ME, Douki T, Valdiglesias V, Laffon B, Fraga S, Brandão F, Herlin-Boime N, Barreau F, Rabilloud T, Carriere M

Toxicological impact of acute exposure to E171 food additive and TiO2 nanoparticles on a co-culture of Caco-2 and HT29-MTX intestinal cells.

Mutat Res, 2019 Sep;845:402980. doi: 10.1016/j.mrgentox.2018.11.004. Epub 2018 Nov 22.
Pereira I, Fraga S, Silva S, Teixeira JP, Gama M

In vitro genotoxicity assessment of an oxidized dextrin-based hydrogel for biomedical applications.

J Appl Toxicol, 2019 Apr;39(4):639-649. doi: 10.1002/jat.3754. Epub 2018 Nov 28.
Leal J, Teixeira-Santos L, Pinho D, Afonso J, Carvalho J, de Lourdes Bastos M, Albino-Teixeira A, Fraga S, Sousa T

l-proline supplementation improves nitric oxide bioavailability and counteracts the blood pressure rise induced by angiotensin II in rats.

Nitric Oxide, 2018 Nov 10. pii: S1089-8603(17)30202-1. doi: 10.1016/j.niox.2018.10.007. [Epub ahead of print]
Esteves FC, Teixeira E, Amorim T, Costa C, Pereira CC, Fraga S, De Andrade VM, Teixeira JP, Costa S

Assessment of DNA damage in a group of professional dancers during a 10-month dancing season.

J Toxicol Environ Health A, 2017 Jul 11:1-8. doi: 10.1080/15287394.2017.1331599. [Epub ahead of print]

Recent developments on Occupational and Environmental Toxicology.

J Toxicol Environ Health A, 2017 Oct 2:1. doi: 10.1080/15287394.2017.1382124. [Epub ahead of print]
Mesquita B, Lopes I, Silva S, Bessa MJ, Starykevich M, Carneiro J, Galvão TLP, Ferreira MGS, Tedim J, Teixeira JP, Fraga S

Gold nanorods induce early embryonic developmental delay and lethality in zebrafish (Danio rerio).

J Toxicol Environ Health A, 2017 Jul 11:1-16. doi: 10.1080/15287394.2017.1331597. [Epub ahead of print]
Bessa MJ, Carla Costa, Reinosa J, Pereira CC, Fraga S, Fernández J, Bañares MA, Teixeira JP

Moving into advanced nanomaterials. Toxicity of rutile TiO2 nanoparticles immobilized in nanokaolin nanocomposites on HepG2 cell line.

Toxicol Appl Pharmacol, 2017 Feb 1;316:114-122. doi: 10.1016/j.taap.2016.12.018. Epub 2016 Dec 28.
Valdiglesias V, Fernández-Bertólez N, Kiliç G, Costa C, Costa S, Fraga S, Bessa MJ, Pásaro E, Teixeira JP, Laffon B

Are iron oxide nanoparticles safe? Current knowledge and future perspectives.

J Trace Elem Med Biol, 2016 Dec;38:53-63. doi: 10.1016/j.jtemb.2016.03.017. Epub 2016 Mar 31.
Quintas C, Fraga S, Gonçalves J, Queiroz G

Opposite modulation of astroglial proliferation by adenosine 5'-O-(2-thio)-diphosphate and 2-methylthioadenosine-5'-diphosphate: mechanisms involved.

Neuroscience, May 19;182:32-42. doi: 10.1016/j.neuroscience.2011.03.009. Epub 2011 Mar 16.
Fraga S, Brandão A, Soares ME, Morais T, Duarte JA, Pereira L, Soares L, Neves C, Pereira E, Bastos Mde L, Carmo H

Short- and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration.

Nanomedicine, Nov;10(8):1757-66. doi: 10.1016/j.nano.2014.06.005. Epub 2014 Jun 15.
Fraga S, Faria H, Soares ME, Duarte JA, Soares L, Pereira E, Costa-Pereira C, Teixeira JP, de Lourdes Bastos M, Carmo H

Influence of the surface coating on the cytotoxicity, genotoxicity and uptake of gold nanoparticles in human HepG2 cells

J Appl Toxicol, 2013, Oct;33(10):1111-9. doi: 10.1002/jat.2865. Epub 2013 Mar 25.
Morais T, Soares ME, Duarte JA, Soares L, Maia S, Gomes P, Pereira E, Fraga S, Carmo H, Bastos Mde L

Effect of surface coating on the biodistribution profile of gold nanoparticles in the rat

Eur J Pharm Biopharm, 2012 Jan;80(1):185-93. doi: 10.1016/j.ejpb.2011.09.005. Epub 2011 Sep 16.
Sousa T, Oliveira S, Afonso J, Morato M, Patinha D, Fraga S, Carvalho F, Albino-Teixeira A

Role of H(2)O(2) in hypertension, renin-angiotensin system activation and renal medullary disfunction caused by angiotensin II

Br J Pharmacol, Aug;166(8):2386-401. doi: 10.1111/j.1476-5381.2012.01957.x.
Quintas C, Fraga S, Gonçalves J, Queiroz G

P2Y receptors on astrocytes and microglia mediate opposite effects in astroglial proliferation

Purinergic Signal, Jun;7(2):251-63. doi: 10.1007/s11302-011-9235-x. Epub 2011 M
Quintas C, Fraga S, Gonçalves J, Queiroz G

The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues.

Neurochem Int, 2009 Dec;55(7):505-13. doi: 10.1016/j.neuint.2009.05.002. Epub 2009 May 15.
Simão S, Fraga S, Jose PA, Soares-da-Silva P

Oxidative stress and alpha1-adrenoceptor-mediated stimulation of the Cl-/HCO3- exchanger in immortalized SHR proximal tubular epithelial cells

Br J Pharmacol, Apr;153(7):1445-55. doi: 10.1038/bjp.2008.16. Epub 2008 Feb 25.
Simão S, Fraga S, Jose PA, Soares-da-Silva P

Oxidative stress plays a permissive role in alpha2-adrenoceptor-mediated events in immortalized SHR proximal tubular epithelial cells.

Mol Cell Biochem, Aug;315(1-2):31-9. doi: 10.1007/s11010-008-9785-6. Epub 2008 May 20.