João Paulo Teixeira

Investigador Doutorado Integrado

Linhas de Investigação: L3 - Determinantes genéticos, ambientais e comportamentais da saúde e da doença

Laboratórios: Poluição do ar e saúde

João Paulo Teixeira é Investigador e responsável da Unidade de Investigação do Departamento de Saúde Ambiental do Instituto Nacional de Saúde (Portugal) desde 2005 e investigador doutorado integrado da EPIUnit-ISPUP.

É Doutorado em Ciências Biomédicas e Mestre em Saúde Pública pela Faculdade de Medicina da Universidade do Porto.
A principal área de actividade científica preocupa-se com os danos genéticos causados por compostos genotóxicos e carcinogénicos, principalmente nas áreas ambiental e ocupacional.

Seu trabalho está focado nos mecanismos moleculares envolvidos na cascata de eventos genotóxicos / carcinogênicos em relação à exposição a xenobióticos, bem como nos fatores de susceptibilidade individual moduladores de efeitos genotóxicos e / ou carcinogénicos. Publicou cerca de 90 artigos científicos e vários capítulos de livros sobre estes temas.

INTERESSES DE INVESTIGAÇÃO
Toxicologia Ambiental, Epidemiologia, Saúde Ocupacional, Biomarcadores, Genotoxicidade, Nanotoxicologia e Qualidade do Ar Interior

ORCID: 0000-0001-8693-5250

Projetos de investigação nacionais

Ano

Título

Artigos

2022

Fernández-Bertólez N , Costa C , Brandão F , Teixeira JP , Pásaro E , Valdiglesias V , Laffon B

Toxicological Aspects of Iron Oxide Nanoparticles

Adv Exp Med Biol, 2022;1357:303-350. doi: 10.1007/978-3-030-88071-2_13. PMID: 35583650.

2022

Correia AS , Fraga S , Teixeira JP , Vale N

Cell Model of Depression: Reduction of Cell Stress with Mirtazapine

, 2022 Apr 29;23(9):4942. doi: 10.3390/ijms23094942.

2022

Sousa AC, Pastorinho MR, Masjedi MR, Urrutia-Pereira M, Arrais M, Nunes E, To T, Ferreira AJ, Robalo-Cordeiro C, Borrego C , Teixeira JP , Taborda-Barata L

Issue 1 - "Update on adverse respiratory effects of outdoor air pollution" Part 2): Outdoor air pollution and respiratory diseases: Perspectives from Angola, Brazil, Canada, Iran, Mozambique and Portugal

Pulmonology, 2022 May 11;S2531-0437(22)00012-5.

2022

Bessa MJ , Brandão F , Fokkens PHB, Leseman DLAC, Boere AJF, Cassee FR, Salmatonidis A, Viana M, Monfort E , Fraga S , Teixeira JP

Unveiling the Toxicity of Fine and Nano-Sized Airborne Particles Generated from Industrial Thermal Spraying Processes in Human Alveolar Epithelial Cells

Int J Mol Sci, 2022 Apr 13;23(8):4278. doi: 10.3390/ijms23084278.

2022

Rosário F , Costa C , Lopes CB, Estrada AC, Tavares DS, Pereira E , Teixeira JP , Reis AT

In Vitro Hepatotoxic and Neurotoxic Effects of Titanium and Cerium Dioxide Nanoparticles, Arsenic and Mercury Co-Exposure

Int J Mol Sci, 2022 Mar 1;23(5):2737. doi: 10.3390/ijms23052737.

2022

Oliveira AS, Rolo J, Gaspar C, Cavaleiro C, Salgueiro L, Palmeira-de-Oliveira R, Ferraz C, Coelho S, Pastorinho MR, Sousa AC , Teixeira JP , Martinez-de-Oliveira J, Palmeira-de-Oliveira A

Chemical characterization and bioactive potential of Thymus×citriodorus (Pers.) Schreb. preparations for anti-acne applications: Antimicrobial, anti-biofilm, anti-inflammatory and safety profiles

J Ethnopharmacol, 2022 Apr 6;287:114935. doi: 10.1016/j.jep.2021.114935. Epub 2021 Dec 24.

2022

Querido M , Rosário F , Bessa MJ , Mendes F , Teixeira JC , Teixeira JP , Pereira CC

In Vitro Cyto- and Genotoxicity Assessment of Antibacterial Paints with Triclosan and Isoborneol

Toxics, 2022 Jan 27;10(2):58. doi: 10.3390/toxics10020058.

2021

Gomes A , Laffon B , Valdiglesias V , Gostner JM, Felder T , Costa C , Madureira J , Fuchs D , Teixeira JP , Costa S

Exploring Early Detection of Frailty Syndrome in Older Adults: Evaluation of Oxi-Immune Markers, Clinical Parameters and Modifiable Risk Factors

Antioxidants (Basel), 2021 Dec 10;10(12):1975. doi: 10.3390/antiox10121975.

2021

Bessa MJ , Brandão F , Fokkens PHB, Leseman DLAC, Boere AJF, Cassee FR, Salmatonidis A, Viana M, Vulpoi A, Simon S, Monfort E , Teixeira JP , Fraga S

In Vitro Toxicity of Industrially Relevant Engineered Nanoparticles in Human Alveolar Epithelial Cells: Air-Liquid Interface versus Submerged Cultures

Nanomaterials (Basel), 2021 Nov 27;11(12):3225. doi: 10.3390/nano11123225.

2021

Querido M , Paulo I, Hariharakrishnan S, Rocha D, Barbosa N, Galhano Dos Santos R, Bordado JM , Teixeira JP , Pereira CC

Self-Disinfecting Paints with the Natural Antimicrobial Substances: Colophony and Curcumin

Antibiotics (Basel), 2021 Nov 5;10(11):1351. doi: 10.3390/antibiotics10111351.

2021

Costa C , Assunção R , Sequeira D , Esteves FC , Valdiglesias V , Laffon B , Teixeira JP , Madureira J

From trihalomethanes chronic daily intake through multiple exposure routes to cancer and non-cancer health risk assessment: Evidence from public Portuguese indoor swimming pools facilities using a probabilistic approach

Sci Total Environ, 2021 Nov 19;151790. doi: 10.1016/j.scitotenv.2021.151790. Online ahead of print.

2021

Moreira L , Costa C , Pires J , Teixeira JP , Fraga S

How can exposure to engineered nanomaterials influence our epigenetic code? A review of the mechanisms and molecular targets

Mutat Res Rev Mutat Res, Jul-Dec 2021;788:108385. doi: 10.1016/j.mrrev.2021.108385. Epub 2021 Jun 12.

2021

Neves CS, Sousa I, Freitas MA, Moreira L, , Costa C , Teixeira JP , Fraga S , Pinto E, Almeida A, Scharnagl N, Zheludkevich ML, Ferreira MGS, Tedim J

Insights into corrosion behaviour of uncoated Mg alloys for biomedical applications in different aqueous media

Journal of Materials Research and Technology, 2021,13:1908-1922; DOI: https://doi.org/10.1016/j.jmrt.2021.05.090

2021

Gongbo Chen, Yuming Guo, Xu Yue, Shilu Tong, Antonio Gasparrini, Michelle L Bell, Ben Armstrong, Joel Schwartz, Jouni J K Jaakkola, Antonella Zanobetti, Eric Lavigne, Paulo Hilario Nascimento , Teixeira JP , Madureira J , Klea Katsouyanni, Magali Hurtado-Díaz, Marek Maasikmets, Martina S Ragettli, Masahiro Hashizume, Massimo Stafoggia, Mathilde Pascal, Matteo Scortichini, Micheline de Sousa Zanotti Stagl

Mortality risk attributable to wildfire-related PM2·5 pollution: a global time series study in 749 locations.

Lancet Planet Health, 2021; 5: e579–87

2021

Fernández-Bertólez N , Brandão F , Costa C , Pásaro E , Teixeira JP , Laffon B

Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO 2 Nanoparticles on SH-SY5Y Cells.

Int J Mol Sci, 2021 Aug 9;22(16):8558. doi: 10.3390/ijms22168558.

2021

Valdiglesias V , Fernández-Bertólez N , Lema-Arranz C, Rodríguez-Fernández R, Pásaro E , Reis AT , Teixeira JP , Costa C , Laffon B

Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage.

Nanomaterials (Basel), 2021 Jul 27;11(8):1930. doi: 10.3390/nano11081930.

2021

Bonassi S, Ceppi M, Møller P, Azqueta A, Milić M, Monica N, Brunborg G, Godschalk R, Koppen G, Langie SAS , Teixeira JP , Bruzzone M, Da Silva J, Benedetti D, Cavallo D, Ursini CL, Giovannelli L, Moretti S, Riso P, Del Bo' C, Russo P, Dobrzyńska M, Goroshinskaya IA, Surikova EI, Staruchova M, Barančokova M, Vol

DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death.

Sci Rep, 2021 Aug 18;11(1):16793. doi: 10.1038/s41598-021-95976-7.

2021

Silva AI , Camelo A , Madureira J , Reis AT , Machado AP , Teixeira JP , Costa C

Urinary cotinine assessment of maternal smoking and environmental tobacco smoke exposure status and its associations with perinatal outcomes: A cross-sectional birth study.

Environ Res, 2021 Aug 4;111827. doi: 10.1016/j.envres.2021.111827. Online ahead of print.

2021

Viana M, Salmatonidis A, Bezantakos S, Ribalta C, Moreno N, Córdoba P, Cassee FR, Boere J , Fraga S , Teixeira JP , Bessa MJ , Monfort E

Characterizing the Chemical Profile of Incidental Ultrafine Particles for Toxicity Assessment Using an Aerosol Concentrator.

Ann Work Expo Health, 2021 Jul 27;wxab011. doi: 10.1093/annweh/wxab011. Online ahead of print.

2021

Brandão F , Costa C , Bessa MJ , Dumortier E, Debacq-Chainiaux F, Hubaux R, Salmon M, Laloy J, Stan MS, Hermenean A, Gharbia S, Dinischiotu A, Bannuscher A, Hellack B, Haase A , Fraga S , Teixeira JP

Genotoxicity and Gene Expression in the Rat Lung Tissue following Instillation and Inhalation of Different Variants of Amorphous Silica Nanomaterials (aSiO 2 NM).

Nanomaterials (Basel), 2021 Jun 7;11(6):1502. doi: 10.3390/nano11061502.