16.07.2018 - 15.07.2022

HIneC “When do health inequalities start? Understanding the impact of childhood social adversity on health trajectories from birth to early adolescence (POCI-01-0145-FEDER—029567)


Financing Instituitions



Begin Date: 16th july 2018

End Date: 15th july 2022


Total Budget: 226.191,85€

Budget attributed to ISPUP: 226.191,85€


Principal Investigator: Sílvia Fraga


Low socioeconomic circumstances during childhood are shown to be associated with negative health outcomes in adulthood, and this effect seem to be independent of the social position achieved in adulthood. Little is known about health inequalities development in early life, particularly, when social inequalities matter most and when interventions may have potential to reverse negative consequences. The question driven of this research project is: “When do health inequalities emerge?”. This research will be integrated in the Generation XXI study, a Portuguese birth cohort established in 2005, involving 8647 babies born in Porto. The first wave took place at birth and participants have been invited to regular follow ups, namely at, 4, 7, 10 and 13 years. In the particular context of Portugal, this approach will provide a unique opportunity to explore when health inequalities start but also to conduct a natural experimental study to analyze the impact of policies adopted during this period as well as the impact of the recent economic recession in children trajectories of life and health.


Weekly Publication

Increase of Antimicrobial Consumption in a Tertiary Care Hospital during the First Phase of the COVID-19 Pandemic.
Antibiotics (Basel)
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