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  • How Changes in Adverse Early Childhood Events Impact Epigenetic Age Acceleration and Psychological Well-Being in Early Adolescence

How Changes in Adverse Early Childhood Events Impact Epigenetic Age Acceleration and Psychological Well-Being in Early Adolescence

Sara Soares

Principal Investigator

Integrated Member (PhD)

Type of project:

National

Reference:

COMPETE2030-FEDER-00924400

Proposing institution:

Prochild

Participating institutions:

Institute of Public Health of the University of Porto (ISPUP)

Sources of financing:

FEDER

Start date:

01/07/2025

(Predicted) End date:

29/06/2028

Total budget:

78 408,00€ (ISPUP Budget)

Research line:

L2 - Syndemics, health inequalities and vulnerable populations

Research lab:

Social Adversity and Health Inequalities

Summary:

Using the Generation21 cohort, we investigate the impact of early-life adversity on pace of epigenetic aging into early adolescence. It examines how psychological adjustment mediates this relationship, aiming to guide public policies and early intervention strategies. With experts on public health, biology, genomics, and psychology, this project promises advancements in understanding the long-term effects of childhood adversity.

PI: Ana Raquel Marcelino Mesquita