ISPUP

Liane Correia Costa completed her Integrated Master in Medicine in 2008 at the Faculty of Medicine of the University of Porto. In 2015, she obtained her PhD degree in Clinical Research and Health Services, by the Faculty of Medicine of the University of Porto, with a thesis entitled “Inflammation related to childhood obesity and injury vascular – impact on the kidney”.

She is a Pediatric assistant and Pediatric Nephrology fellow at Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, since 2016.

She was a Voluntary Assistant Professor of Pediatrics of Faculty of Medicine, University of Porto, from 2010 to 2016 and, currently, she is Assistant Professor of Pediatrics at Instituto de Ciências Biomédicas de Abel Salazar, University of Porto, since 2016.

She is the coordinator of the Education and Research Unit at Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto. Her main research interests are obesity and cardiovascular risk and chronic kidney disease determinants in children, areas in which she has several publications in international peer-reviewed journals.

National research projects

Year

Title

Articles

2021

Morais J , Soares S , Costa L , Santos AC , Barreira JL

Determinants of bedwetting trajectories between 4 and 7 years - A birth cohort analysis

J Pediatr Urol, 2021 Oct;17(5):647.e1-647.e10. doi: 10.1016/j.jpurol.2021.07.031. Epub 2021 Aug 19.

2021

Pinto FR, Alexandrino AS , Costa L , Azevedo I

Ambulatory chest physiotherapy in mild-to-moderate acute bronchiolitis in children under two years of age - A randomized control trial.

Hong Kong Physiother J, 2021 Dec;41(2):99-108. doi: 10.1142/S1013702521500098. Epub 2021 Mar 31.

2021

Leite-Almeida L, Morato M, Cosme D, Afonso J, Areias JC, Guerra A , Caldas-Afonso A , Albino-Teixeira A, Sousa T , Costa L

Impact of physical activity on redox status and nitric oxide bioavailability in nonoverweight and overweight/obese prepubertal children.

Free Radic Biol Med, 2021 Feb 1;163:116-124. doi: 10.1016/j.freeradbiomed.2020.12.005. Epub 2020 Dec 11.

2020

Pinto FR , Costa L , Azevedo I

Comparison of Kristjansson Respiratory Score and Wang Respiratory Score in infants with bronchiolitis in a hospital emergency department.

Hong Kong Physiother J, 2020 Dec;40(2):145-153. doi: 10.1142/S1013702520500146. Epub 2020 Aug 21.

2020

Ribeiro AI , Fraga S , Costa L , McCrory C , Barros H

Socioeconomic disadvantage and health in early childhood: a population-based birth cohort study from Portugal.

Pediatr Res, 2020 Jan 31. doi: 10.1038/s41390-020-0786-9. [Epub ahead of print]

2019

Costa L , Schaefer F , Caldas-Afonso A , Correia S , Guimarães JT , Guerra A , Barros H , Azevedo A

Prenatal alcohol exposure affects renal function in overweight schoolchildren: birth cohort analysis.

Pediatr Nephrol, 2019 Dec 9. doi: 10.1007/s00467-019-04429-x. [Epub ahead of print]

2018

Costa L , Azevedo A , Caldas-Afonso A

Childhood Obesity and Impact on the Kidney.

Nephron, 2018 Oct 25:1-4. doi: 10.1159/000492826. [Epub ahead of print]

2018

Adlbrecht C, Blanco-Verea A, Bouzas-Mosquera MC, Brion M, Burtscher M, Carbone F, Chang TT, Charmandari E, Chen JW , Costa L , Dullaart RPF, Eleftheriades M, Fernandez-Fernandez B, Goliasch G, Gremmel T, Groeneveld ME, Henrique A, Huelsmann M, Jung C, Lichtenauer M, Montecucco F, Nicolaides NC, Niessner A, Palmeira C,

Research update for articles published in EJCI in 2016.

Eur J Clin Invest, 2018 Aug 12:e13016. doi: 10.1111/eci.13016. [Epub ahead of print]

2018

Cabral M , Fonseca MJ , González-Beiras C , Santos AC , Costa L , Barros H

Maternal smoking: a life course blood pressure determinant?

Nicotine Tob Res, 2018 May 3;20(6):674-680. doi: 10.1093/ntr/ntx117

2017

Morato M , Costa L , Sousa T , Cosme D , Schaefer F , Areias JC , Guerra A , Caldas-Afonso A , Barros H , Azevedo A , Albino-Teixeira A

Longer duration of obesity is associated with a reduction in urinary angiotensinogen in prepubertal children.

, 2017 Mar 23. doi: 10.1007/s00467-017-3639-y. [Epub ahead of print]

2016

Costa L , Sousa T , Morato M , Cosme D , Afonso J , Areias JC , Schaefer F , Guerra A , Caldas-Afonso A , Azevedo A , Albino-Teixeira A

Oxidative stress and nitric oxide are increased in obese children and correlate with cardiometabolic risk and renal function.

Br J Nutr, 2016 Sep;116(5):805-15. doi: 10.1017/S0007114516002804. Epub 2016 Aug 2.

2016

Correia-Costa A , Costa L , Caldas-Afonso A , Schaefer F , Guerra A , Moura C , Mota C , Barros H , Areias JC , Azevedo A

Determinants of carotid-femoral pulse wave velocity in prepubertal children.

Int J Cardiol, 2016 Sep 1;218:37-42. doi: 10.1016/j.ijcard.2016.05.060. Epub 2016 May 14.

2016

Costa L , Schaefer F , Afonso AC , Bustorff M , Guimarães JT , Guerra A , Barros H , Azevedo A

Normalization of glomerular filtration rate in obese children.

, 2016 Mar 23. [Epub ahead of print]

2016

Costa L , Morato M , Sousa T , Cosme D , Guimarães JT , Guerra A , Schaefer F , Afonso AC , Azevedo A , Albino-Teixeira A

Urinary fibrogenic cytokines ET-1 and TGF-β1 are associated with urinary angiotensinogen levels in obese children

Pediatr Nephrol, 2016 Mar;31(3):455-64. doi: 10.1007/s00467-015-3232-1. Epub 2015 Oct 19.

2016

Pais C , Costa L , Moura C , Mota C , Severo M , Guerra A , Areias JC , Schaefer F , Caldas-Afonso A , Barros H , Santos AC , Azevedo A

Accelerated growth during childhood is associated with increased arterial stiffness in prepubertal children.

Int J Cardiol, 2016 Feb 1;204:83-5. doi: 10.1016/j.ijcard.2015.11.149. Epub 2015 Nov 23.

2016

Costa L , Cosme D , Nogueira-Silva L , Morato M , Sousa T , Moura C , Mota C , Guerra A , Albino-Teixeira A , Schaefer F , Lopes C , Caldas-Afonso A , Azevedo A

Gender and obesity modify the impact of salt intake on blood pressure in children.

Pediatr Nephrol, 2016 Feb;31(2):279-88. doi: 10.1007/s00467-015-3210-7. Epub 2015 Sep 29.

2016

Costa L , Sousa T , Morato M , Cosme D , Afonso J , Moura C , Mota C , Areias JC , Guerra A , Schaefer F , Afonso AC , Barros H , Albino-Teixeira A , Azevedo A

Association of myeloperoxidase levels with cardiometabolic factors and renal function in prepubertal children

Eur J Clin Invest, 2016 Jan;46(1):50-9. doi: 10.1111/eci.12564. Epub 2015 Dec 1.

2015

Costa L , Santos AC , Severo M , Guerra A , Azevedo A , Caldas-Afonso A , Barros H , Schaefer F

Sex-Specific Mediating Role of Insulin Resistance and Inflammation in the Effect of Adiposity on Blood Pressure of Prepubertal Children

PLoS One, 2015 Jun 30;10(6):e0132097. doi: 10.1371/journal.pone.0132097. eCollection 2015.

2015

Costa L , Caldas-Afonso A , Schaefer F , Guimarães JT , Bustorff M , Guerra A , Barros H , Azevedo A

Decreased renal function in overweight and obese prepubertal children

Pediatric Research, 2015 Oct;78(4):436-44. doi: 10.1038/pr.2015.130. Epub 2015 Jul 7.

2015

Aguiar C , Costa L , Eden P , Guedes-Vaz L

Cystic fibrosis and beckwith-wiedemann syndrome: a case report.

J Clin Med Res., 2015 Mar;7(3):186-8. doi: 10.14740/jocmr2003w. Epub 2014 Dec 29.

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Liane Costa

Integrated Member (PhD)

National research projects

Articles

Books

Book Chapters

Notices/Letters to the Editor

Reports