Digital Public Health Solutions for Response to COVID-19

Vítor Tedim Cruz

Principal Investigator

Integrated Member (PhD)

Type of project:




Participating institutions:

NeuroInova, Lda; ULS Matosinhos, EPE; CHEDV, EPE;

Sources of financing:

Calouste Gulbenkian Foundation

Start date:


(Predicted) End date:


Total budget:

9.850,00 €

Research line:

L4 - Patient and Population Outcomes Research

Research lab:

Cognitive Impairment in Diseases Involving the Nervous System



SARS-CoV-2 has been shown to be neurotropic, accessing the brain via cranial nerves and diffusing by synaptic transfer. This feature can aggravate encephalopathy after severe acute respiratory illness, or anticipate the development of quiescent neurodegenerative diseases (e.g.: Alzheimer’s or Parkinson’s disease). It is therefore essential to implement an epidemiological surveillance model of the cognitive performance of individuals after SARS-CoV-2 infection. Considering the context of isolation and the need to monitor a high number of
individuals for long periods of time, this will only be sustainable using a self-administered digital instrument. ISPUP has developed an instrument with these characteristics – Brain on Track – to assess cognitive trajectories, in Portugal, in early models of dementia, multiple sclerosis and cancer survivors, and in Sweden (Upsala University), in a cognitive monitoring model after Tundra encephalitis.

Research team